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Complement 3 Glomerulopathy Market Insights, Epidemiology, and Market Forecast-2030

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Complement 3 Glomerulopathy Market Insights, Epidemiology, and Market Forecast-2030

July 30
09:32 2020
Complement 3 Glomerulopathy Market Insights, Epidemiology, and Market Forecast-2030

(Albany, US) Delveinsight has launched a new report on Complement 3 Glomerulopathy Market

DelveInsight’s Complement 3 Glomerulopathy Market Insights, Epidemiology, and Market Forecast-2030 report delivers an in-depth understanding of the Complement 3 Glomerulopathy (C3G) , historical and forecasted epidemiology as well as the Complement 3 Glomerulopathy (C3G) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Complement 3 Glomerulopathy market report provides current treatment practices, emerging drugs, Complement 3 Glomerulopathy (C3G) market share of the individual therapies, current and forecasted Complement 3 Glomerulopathy (C3G) market Size from 2017 to 2030 segmented by seven major markets. The Report also covers current Complement 3 Glomerulopathy (C3G) treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market

Complement 3 glomerulopathy (C3G) was adopted by expert consensus in 2013 to define a group of rare kidneys diseases driven by dysregulation of the complement cascade. It is a type of glomerular disease, characterized by predominant C3 complement component (C3) deposits in the glomeruli in the absence of a significant amount of immunoglobulin and without deposition of C1q and C4.  The term C3G includes dense deposit disease (DDD) and C3 glomerulonephritis (C3GN), which are the two patterns of damage and inflammation in the glomeruli. In other words, the damage and inflammation in the kidney tissue in DDD appear different from that in C3GN when observed under a microscope. People with DDD generally present at a younger age (childhood or adolescence) compared to people with C3GN (adulthood).  In DDD, C3 deposits are bunched up in one area of the glomeruli and appear thick while in case of C3GN, C3 deposits are more spread out and less thick. Progression to end-stage renal disease (ESRD) has been found in 40% of C3G patients, with no detectable difference between those with C3GN versus DDD. Dysregulation of the complement alternative pathway, driven by acquired and/or genetic defects, plays a pathogenetic role in C3G. However, alternative pathway abnormalities are also found in IC-MPGN (immune-complex-MPGN). The most common acquired drivers of C3G are the C3 nephritic factors (C3NeFs),heterogeneous autoantibodies that stabilize the C3 convertase, C3bBb.

Request for free sample page:- https://www.delveinsight.com/sample-request/complement-3-glomerulopathy-c3g-market

Complement 3 Glomerulopathy Treatment Market

The DelveInsight Complement 3 Glomerulopathy market report gives a thorough understanding of the Complement 3 Glomerulopathy (C3G) by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis and treatment. This segment of the report covers the detailed diagnostic methods or tests for Complement 3 Glomerulopathy (C3G).  It covers the details of conventional and current medical therapies available in the Complement 3 Glomerulopathy (C3G) market for the treatment of the condition. It also provides Complement 3 Glomerulopathy (C3G) treatment algorithms and guidelines in the United States, Europe, and Japan.

Complement 3 Glomerulopathy Market

Optimal treatment for C3G has not been established yet since no treatment has proven effective and beneficial for C3G. Recommendations have only been deducted from case series and observational studies and are mostly based on expert opinion. As a consequence, its treatment has not been standardized and is concentrated in centres of expertise. All patients diagnosed with C3G should be treated with renoprotective measures, including lifestyle advice, an angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker to control hypertension and proteinuria, and lipid-lowering treatment. Such medication alone has not been shown to protect against progression to end-stage renal disease but may improve the protective effect of immunosuppressive medication.

Since there are no approved therapies for C3G, the market is mainly dominated by the use of off-label prescription drugs. Treatments for C3G include Immunosuppressant, Steroids, Renin–angiotensin–aldosterone system Inhibitors (RAAS), and other Supportive therapies (also including Antibody regimens: Eculizumab and Rituximab). The current emerging market of C3G possesses an intermediate pipeline. Expected Launch of potential therapies, Danicopan (Alexion Pharmaceuticals), Narsoplimab (Omeros Corporation), Pegcetacoplan (Apellis Pharmaceuticals), ChemoCentryx (Avacopan; Phase II), and LNP023 (Novartis Pharmaceuticals) during the forecast period of 2020-2030, may increase the market size in the coming years, assisted by an increase in diagnosed prevalent population of C3G. In addition, there are few early stage key players, namely, Amyndas Pharmaceuticals (AMY-101; Phase I) and Visterra Inc.(Preclinical Stage) that are investigating their drug candidates for the treatment of patients with C3G as well. Since there are no approved therapies for C3G, the market is mainly dominated by the use of off-label prescription drugs. Treatments for C3G include Immunosuppressant, Steroids, Renin–angiotensin–aldosterone system Inhibitors(RAAS), and other Supportive therapies (also including Antibody regimens: Eculizumab and Rituximab). The current emerging market of C3G possesses an intermediate pipeline. Expected Launch of potential therapies,Danicopan (Alexion Pharmaceuticals), Narsoplimab (Omeros Corporation), Pegcetacoplan (Apellis Pharmaceuticals),ChemoCentryx (Avacopan; Phase II), and LNP023 (Novartis Pharmaceuticals) during the forecast period of 2020-2030,may increase the market size in the coming years, assisted by an increase in diagnosed prevalent population of C3G. In addition, there are few early stage key players, namely, Amyndas Pharmaceuticals (AMY-101; Phase I) and Visterra Inc.(Preclinical Stage) that are investigating their drug candidates for the treatment of patients with C3G as well.

Scope of the Report

  • The report covers the descriptive overview of Complement 3 Glomerulopathy (C3G) , explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
  • Comprehensive insight has been provided into the Complement 3 Glomerulopathy (C3G) epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for Complement 3 Glomerulopathy (C3G) are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
  • A detailed review of Complement 3 Glomerulopathy (C3G) market; historical and forecasted is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Complement 3 Glomerulopathy (C3G) market

 

 Request for free sample page:- https://www.delveinsight.com/sample-request/complement-3-glomerulopathy-c3g-market

 

Table of content

1. Key Insights

2. Executive Summary of Complement 3 Glomerulopathy (C3G)

3. Competitive Intelligence Analysis for Complement 3 Glomerulopathy (C3G)

4. Complement 3 Glomerulopathy (C3G) : Market Overview at a Glance

5. Complement 3 Glomerulopathy (C3G) : Disease Background and Overview

6. Patient Journey

7. Complement 3 Glomerulopathy (C3G) Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Unmet Needs

10. Key Endpoints of Complement 3 Glomerulopathy (C3G) Treatment

11. Marketed Products

12. Emerging Therapies

13. Complement 3 Glomerulopathy (C3G) : Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Complement 3 Glomerulopathy (C3G)

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight

 

Why should you buy this report?

  • The report will help in developing business strategies by understanding trends shaping and driving the Complement 3 Glomerulopathy (C3G) market
  • To understand the future market competition in the Complement 3 Glomerulopathy (C3G) market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Complement 3 Glomerulopathy (C3G) in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Complement 3 Glomerulopathy (C3G) market
  • To understand the future market competition in the Complement 3 Glomerulopathy (C3G) market

 

Related Reports

Complement 3 Glomerulopathy Market Insight, Epidemiology and Market Forecast -2030

Complement 3 Glomerulopathy (C3G) Epidemiology Forecast to 2030

 

About Us

DelveInsight is a Business Consulting and Market research company, providing expert business solutions for life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.

 

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